2017 US Open – Men's singles

Rafael Nadal defeated Kevin Anderson in the final, 6–3, 6–3, 6–4 to win the men's singles tennis title at the 2017 US Open. It was his third US Open title and 16th major title overall. It was also his first hard court title since January 2014.

Stan Wawrinka was the reigning champion, but did not participate due to a knee injury that ended his season prematurely. Wawrinka's withdrawal ended his streak of 50 consecutive major appearances, dating back to the 2005 French Open. Reigning finalist Novak Djokovic also withdrew due to an elbow injury that ended his season, ending his streak of 51 consecutive major appearances, dating back to the 2005 Australian Open. Accordingly, this was the first men's singles draw at the US Open since 1971 to include neither finalist from the previous year's tournament.

After the loss of Marin Čilić in the third round, a first-time major finalist was guaranteed from the bottom half of the draw. Anderson was the first South African man to reach the final since Cliff Drysdale in 1965, and at any major singles final since Kevin Curren at the 1984 Australian Open, as well as the lowest-ranked man to reach the US Open singles final since the ATP rankings began in 1973. Anderson was also the tallest major finalist in history, at 6 feet 8 inches.

Nadal, Roger Federer and Andy Murray were in contention for the world No. 1 singles ranking at the start of the tournament. Nadal retained the top ranking following Murray's withdrawal and Federer's loss in the quarterfinals.

Federer broke the men's singles record for total appearances at majors with his 71st participation. He was attempting to go undefeated at the majors for the season (having won the Australian Open and Wimbledon Championships and not played the French Open), but lost to Juan Martín del Potro in the quarterfinals. Andrey Rublev became the youngest man to reach the US Open quarterfinals since Andy Roddick in 2001, and Denis Shapovalov became the youngest man to reach the fourth round of the US Open since Michael Chang in 1989. Sam Querrey became the first American man to reach the quarterfinals of the US Open since John Isner and Andy Roddick in 2011. Diego Schwartzman became the shortest man (5 feet 7 inches) to reach a major singles quarterfinal since Jaime Yzaga (also 5 feet 7 inches) at the 1994 US Open.

This tournament marked the first US Open main draw appearance of future world No. 1 and 2021 US Open champion Daniil Medvedev; he lost in the first round to Shapovalov.

Seeds
• 🇪🇸 Rafael Nadal (champion)

• 🇬🇧 Andy Murray (withdrew due to a hip injury)

• Roger Federer (quarterfinals)

• 🇩🇪 Alexander Zverev (second round)

•  Marin Čilić (third round)

• 🇦🇹 Dominic Thiem (fourth round)

• 🇧🇬 Grigor Dimitrov (second round)

• 🇫🇷 Jo-Wilfried Tsonga (second round)

• 🇧🇪 David Goffin (fourth round)

• 🇺🇸 John Isner (third round)

• 🇪🇸 Roberto Bautista Agut (third round)

• 🇪🇸 Pablo Carreño Busta (semifinals)

• 🇺🇸 Jack Sock (first round)

• 🇦🇺 Nick Kyrgios (first round)

• 🇨🇿 Tomáš Berdych (second round)

• 🇫🇷 Lucas Pouille (fourth round)

• 🇺🇸 Sam Querrey (quarterfinals)

• 🇫🇷 Gaël Monfils (third round, retired)

• 🇱🇺 Gilles Müller (second round)

• 🇪🇸 Albert Ramos Viñolas (second round)

• 🇪🇸 David Ferrer (first round)

• 🇮🇹 Fabio Fognini (first round)

• 🇩🇪 Mischa Zverev (fourth round)

• 🇦🇷 Juan Martín del Potro (semifinals)

• 🇷🇺 Karen Khachanov (first round)

• 🇫🇷 Richard Gasquet (first round)

•  Pablo Cuevas (first round)

•  Kevin Anderson (final)

• 🇦🇷 Diego Schwartzman (quarterfinals)

• 🇫🇷 Adrian Mannarino (third round)

• 🇪🇸 Feliciano López (third round)

•  Robin Haase (first round)

• 🇩🇪 Philipp Kohlschreiber (fourth round)

Seeded players
The following are the seeded players. Seeds are based on the rankings as of August 21, 2017. Rank and points before are as of August 28, 2017.

Withdrawn players
The following players would have been seeded, but withdrew before the tournament began.

Wild cards
• 🇫🇷 Geoffrey Blancaneaux

• 🇦🇺 Alex De Minaur

• 🇺🇸 Christopher Eubanks

• 🇺🇸 Bjorn Fratangelo

• 🇺🇸 Taylor Fritz

• 🇺🇸 Thai-Son Kwiatkowski

• 🇺🇸 Patrick Kypson

• 🇺🇸 Tommy Paul

Protected ranking
• 🇱🇹 Ričardas Berankis (92)

• Ernests Gulbis (99)

• 🇦🇹 Andreas Haider-Maurer (63)

• 🇦🇺 Thanasi Kokkinakis (81)

• 🇦🇺 John Millman (81)

• 🇷🇺 Dmitry Tursunov (89)

Qualifiers
• 🇲🇩 Radu Albot

• 🇺🇸 JC Aragone

• Darian King

• 🇺🇸 Evan King

• 🇰🇿 Mikhail Kukushkin

• 🇫🇷 Nicolas Mahut

• 🇩🇪 Maximilian Marterer

• 🇪🇸 Adrián Menéndez-Maceiras

• 🇫🇷 Vincent Millot

• 🇬🇧 Cameron Norrie

• 🇨🇿 Václav Šafránek

• 🇨🇦 Denis Shapovalov

• 🇦🇺 John-Patrick Smith

• 🇺🇸 Tim Smyczek

• 🇩🇪 Cedrik-Marcel Stebe

• 🇮🇹 Stefano Travaglia

Lucky losers
• 🇸🇰 Lukáš Lacko

• 🇦🇷 Leonardo Mayer

Withdrawals
• 🇬🇧 Dan Evans (60) → replaced by Ernests Gulbis (99 PR)

• 🇷🇸 Novak Djokovic (4) → replaced by  Henri Laaksonen (100)

• 🇯🇵 Yoshihito Nishioka (90) → replaced by 🇺🇸 Tennys Sandgren (101)

•  Stan Wawrinka (5) → replaced by 🇩🇪 Florian Mayer (102)

• 🇯🇵 Kei Nishikori (8) → replaced by 🇧🇷 Thiago Monteiro (103)

• 🇦🇷 Federico Delbonis (84) → replaced by 🇮🇹 Alessandro Giannessi (104)

• 🇨🇦 Milos Raonic (9) → replaced by 🇦🇷 Leonardo Mayer (LL)

• 🇬🇧 Andy Murray (1) → replaced by 🇸🇰 Lukáš Lacko (LL)

Retirements
• 🇬🇧 Kyle Edmund

• 🇨🇴 Santiago Giraldo

• 🇦🇹 Andreas Haider-Maurer

• 🇫🇷 Gaël Monfils

• 🇨🇦 Vasek Pospisil

• 🇷🇺 Dmitry Tursunov