2016 US Open – Men's singles

Stan Wawrinka defeated the defending champion Novak Djokovic in the final, 6–7(1–7), 6–4, 7–5, 6–3 to win the men's singles tennis title at the 2016 US Open. It was his first US Open title, and third major title overall. On all three occasions, he defeated the world No. 1 player in the final. Wawrinka saved a match point en route to the title, against Dan Evans in the third round. Djokovic became the third man in the Open Era (after Ivan Lendl and Andy Murray) to lose five finals at the same major.

This was the first US Open since 1999 not to feature five-time champion Roger Federer. This was the first major that Tomáš Berdych, then the world No. 8, missed ever since his debut at the 2003 US Open, ending his streak of 52 consecutive Grand Slam appearances (sixth-highest of all-time).

No American player was seeded inside the top 16 for the first time since the introduction of the seeding system in 1930. Steve Johnson was the top-seeded American man at No. 19.

Seeds
• 🇷🇸 Novak Djokovic (final)

• 🇬🇧 Andy Murray (quarterfinals)

•  Stan Wawrinka (champion)

• 🇪🇸 Rafael Nadal (fourth round)

• 🇨🇦 Milos Raonic (second round)

• 🇯🇵 Kei Nishikori (semifinals)

• Marin Čilić (third round)

• 🇦🇹 Dominic Thiem (fourth round, retired)

• 🇫🇷 Jo-Wilfried Tsonga (quarterfinals, retired)

• 🇫🇷 Gaël Monfils (semifinals)

• 🇪🇸 David Ferrer (third round)

• 🇧🇪 David Goffin (first round)

• 🇫🇷 Richard Gasquet (first round)

• 🇦🇺 Nick Kyrgios (third round, retired)

• 🇪🇸 Roberto Bautista Agut (third round)

• 🇪🇸 Feliciano López (second round)

• 🇦🇺 Bernard Tomic (first round)

•  Pablo Cuevas (second round)

• 🇺🇸 Steve Johnson (second round)

• 🇺🇸 John Isner (third round)

•  Ivo Karlović (fourth round)

• 🇧🇬 Grigor Dimitrov (fourth round)

•  Kevin Anderson (third round)

• 🇫🇷 Lucas Pouille (quarterfinals)

• 🇩🇪 Philipp Kohlschreiber (first round, retired)

• 🇺🇸 Jack Sock (fourth round)

• 🇩🇪 Alexander Zverev (second round)

• 🇸🇰 Martin Kližan (first round)

• 🇺🇸 Sam Querrey (first round)

• 🇫🇷 Gilles Simon (second round)

• 🇪🇸 Albert Ramos Viñolas (second round)

• 🇫🇷 Benoît Paire (second round)

Seeded players
Seeds are based on the ATP and WTA rankings as of August 22, 2016. Rank and points before are as of August 29, 2016.

Withdrawn players
The following players would have been seeded, but they withdrew from the event.

Wild cards
• 🇦🇷 Juan Martín del Potro

• 🇦🇺 James Duckworth

• 🇺🇸 Ernesto Escobedo

• 🇺🇸 Bjorn Fratangelo

• 🇺🇸 Mackenzie McDonald

• 🇺🇸 Michael Mmoh

• 🇺🇸 Rajeev Ram

• 🇺🇸 Frances Tiafoe

Protected ranking
• 🇺🇸 Brian Baker (56)

• 🇫🇷 Julien Benneteau (39)

• 🇵🇱 Jerzy Janowicz (94)

• 🇷🇸 Janko Tipsarević (39)

• 🇷🇺 Dmitry Tursunov (89)

Qualifiers
• 🇦🇷 Guido Andreozzi

• Marco Chiudinelli

• 🇧🇷 Guilherme Clezar

• 🇧🇪 Steve Darcis

• 🇺🇸 Jared Donaldson

• 🇮🇹 Thomas Fabbiano

• 🇭🇺 Márton Fucsovics

• 🇮🇹 Alessandro Giannessi

• 🇺🇸 Christian Harrison

• 🇺🇸 Ryan Harrison

• 🇧🇾 Ilya Ivashka

• 🇷🇺 Karen Khachanov

• 🇮🇳 Saketh Myneni

• 🇨🇿 Jan Šátral

• 🇨🇿 Radek Štěpánek

• 🇩🇪 Mischa Zverev

Lucky losers
• 🇩🇪 Daniel Brands

• 🇸🇰 Jozef Kovalík

Withdrawals
• Roger Federer (3) → replaced by 🇩🇪 Dustin Brown (99)
 * Before the tournament

• 🇪🇸 Tommy Robredo (92) → replaced by 🇷🇺 Teymuraz Gabashvili (100)

•  Ernests Gulbis (64) → replaced by 🇺🇸 Denis Kudla (101)

• 🇨🇿 Tomáš Berdych (8) → replaced by 🇸🇰 Lukáš Lacko (102)

• 🇦🇺 Thanasi Kokkinakis (81 PR) → replaced by 🇸🇰 Jozef Kovalík (LL)

• 🇷🇺 Dmitry Tursunov (89 PR) → replaced by 🇩🇪 Daniel Brands (LL)


 * During the tournament
 * 🇨🇿 Jiří Veselý (left forearm inflammation)

• 🇦🇷 Facundo Bagnis
 * Retirements

• Borna Ćorić

• 🇺🇦 Alexandr Dolgopolov

• 🇩🇪 Philipp Kohlschreiber

• 🇦🇺 Nick Kyrgios

• 🇸🇰 Lukáš Lacko

• 🇦🇹 Dominic Thiem

• 🇫🇷 Jo-Wilfried Tsonga

• 🇷🇺 Mikhail Youzhny