2004 French Open – Women's singles

Anastasia Myskina defeated Elena Dementieva in the final, 6–1, 6–2 to win the women's singles tennis title at the 2004 French Open. It was her first and only major title, and she became the first Russian woman to win a singles major. Myskina became the first woman in the Open Era to win the French Open after saving a match point, doing so in the fourth round against Svetlana Kuznetsova. This marked the first major final contested by two first-time finalists since the 1979 Australian Open. The final also made Russia the fourth country in the Open Era (following Australia, the United States, and Belgium) to have two countrywomen contest a major final.

Justine Henin-Hardenne was the defending champion, but lost in the second round to Tathiana Garbin. This was her only loss at the French Open between 2003 and 2007.

This marked the first major in which future two-time French Open champion Maria Sharapova reached the quarterfinals.

Martina Navratilova played in her first major since 1994, being unseeded for the first time since the 1973 US Open. Awarded a wild card, it was her final French Open singles appearance; she lost in the first round to Gisela Dulko.

Seeds
• # 🇧🇪 Justine Henin-Hardenne (second round)

• # 🇺🇸 Serena Williams (quarterfinals)

• # 🇫🇷 Amélie Mauresmo (quarterfinals)

• # 🇺🇸 Venus Williams (quarterfinals)

• # 🇺🇸 Lindsay Davenport (fourth round)

• # 🇷🇺 Anastasia Myskina (champion)

• # 🇺🇸 Jennifer Capriati (semifinals)

• # 🇷🇺 Nadia Petrova (third round)

• # 🇷🇺 Elena Dementieva (final)

• # 🇷🇺 Vera Zvonareva (third round)

• # 🇷🇺 Svetlana Kuznetsova (fourth round)

• # 🇯🇵 Ai Sugiyama (second round)

• # 🇺🇸 Chanda Rubin (withdrew)

• # 🇦🇷 Paola Suárez (semifinals)

• # 🇮🇹 Silvia Farina Elia (second round)

• # Patty Schnyder (second round)

• # 🇮🇹 Francesca Schiavone (fourth round)

• # 🇷🇺 Maria Sharapova (quarterfinals)

• # 🇮🇱 Anna Smashnova-Pistolesi (third round)

• # 🇪🇸 Conchita Martínez (second round)

• # 🇧🇬 Magdalena Maleeva (fourth round)

• # Karolina Šprem (first round)

• # 🇨🇴 Fabiola Zuluaga (fourth round)

• # Jelena Dokić (first round)

• # 🇷🇺 Elena Bovina (third round)

• # 🇫🇷 Nathalie Dechy (first round)

• # Eleni Daniilidou (first round)

• # 🇺🇸 Lisa Raymond (second round)

• # 🇭🇺 Petra Mandula (second round)

• # 🇫🇷 Mary Pierce (third round)

• # 🇫🇷 Émilie Loit (second round)

• # 🇷🇺 Dinara Safina (second round)