2004 Australian Open – Women's singles

Justine Henin-Hardenne defeated Kim Clijsters in the final, 6–3, 4–6, 6–3 to win the women's singles tennis title at the 2004 Australian Open. It was her third major title, each time defeating Clijsters in the final (after her victories at the 2003 French and US Opens). Clijsters would eventually win the title seven years later.

Serena Williams was the reigning champion, but did not participate this year due to a left knee injury.

Fabiola Zuluaga became the first Colombian to reach a major semifinal.

Seeds
• # 🇧🇪 Justine Henin-Hardenne (champion)

• # 🇧🇪 Kim Clijsters (final)

• # 🇺🇸 Venus Williams (third round)

• # 🇫🇷 Amélie Mauresmo (quarterfinals, withdrew)

• # 🇺🇸 Lindsay Davenport (quarterfinals)

• # 🇷🇺 Anastasia Myskina (quarterfinals)

• # 🇷🇺 Elena Dementieva (first round)

• # 🇯🇵 Ai Sugiyama (second round)

• # 🇺🇸 Chanda Rubin (fourth round)

• # 🇷🇺 Nadia Petrova (first round)

• # 🇷🇺 Vera Zvonareva (fourth round)

• # 🇦🇷 Paola Suárez (third round)

• # 🇪🇸 Conchita Martínez (first round)

• # 🇮🇱 Anna Smashnova-Pistolesi (second round)

• # 🇸🇰 Daniela Hantuchová (second round)

• # 🇪🇸 Magüi Serna (first round)

• # 🇺🇸 Meghann Shaughnessy (first round)

• # 🇮🇹 Francesca Schiavone (second round)

• # Eleni Daniilidou (third round)

• # 🇮🇹 Silvia Farina Elia (fourth round)

• # 🇷🇺 Elena Bovina (second round)

• # Patty Schnyder (semifinals)

• # 🇷🇺 Lina Krasnoroutskaya (third round)

• # 🇧🇬 Magdalena Maleeva (second round)

• # 🇺🇸 Lisa Raymond (quarterfinals)

• # Tina Pisnik (first round)

• # Amanda Coetzer (second round)

• # 🇷🇺 Maria Sharapova (third round)

• # 🇫🇷 Nathalie Dechy (fourth round)

• # 🇷🇺 Svetlana Kuznetsova (third round)

• # 🇹🇭 Tamarine Tanasugarn (first round)

• # 🇨🇴 Fabiola Zuluaga (semifinals)