2022 Santa Cruz Challenger

The 2022 Santa Cruz Challenger, also known as Dove MEN + CARE Challenger Bolivia, was a professional tennis tournament played on clay courts. It was the first edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Santa Cruz de la Sierra, Bolivia between 24 and 30 January 2022.

Seeds

 * 1 Rankings are as of 17 January 2022.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇧🇴 Boris Arias
 * 🇧🇴 Murkel Dellien
 * 🇧🇴 Federico Zeballos

The following player received entry into the singles main draw as an alternate:
 * 🇵🇪 Nicolás Álvarez

The following players received entry from the qualifying draw:
 * 🇦🇷 Pedro Cachin
 * 🇦🇷 Matías Franco Descotte
 * 🇪🇨 Diego Hidalgo
 * 🇧🇴 Juan Carlos Prado Ángelo
 * 🇨🇴 Cristian Rodríguez
 * 🇦🇷 Gonzalo Villanueva

The following player received entry as a lucky loser:
 * Michel Vernier

Singles

 * 🇦🇷 Francisco Cerúndolo def. 🇦🇷 Camilo Ugo Carabelli 6–4, 6–3.

Doubles

 * 🇪🇨 Diego Hidalgo / 🇨🇴 Cristian Rodríguez def. 🇸🇰 Andrej Martin / 🇦🇹 Tristan-Samuel Weissborn 4–6, 6–3, [10–8].