2001 Kremlin Cup – Men's singles

The 2001 Kremlin Cup men's singles was a professional tennis competition. Yevgeny Kafelnikov was the defending champion and won in the final 6–4, 7–5 against Nicolas Kiefer.

Seeds
• # 🇷🇺 Yevgeny Kafelnikov (champion)

• # 🇷🇺 Marat Safin (second round)

• # Roger Federer (first round)

• # 🇩🇪 Tommy Haas (semifinals)

• # 🇸🇪 Thomas Johansson (quarterfinals)

• # 🇫🇷 Fabrice Santoro (second round)

• # 🇦🇷 Guillermo Cañas (second round)

• # 🇫🇷 Nicolas Escudé (first round)