2021 LTP Women's Open

The 2021 LTP Women's Open was a professional tennis tournament played on outdoor green clay courts. It was the 1st edition of the tournament and part of the 2021 WTA 125K series, offering a total of $115,000 in prize money. It took place in Charleston, South Carolina, United States from 26 July to 1 August 2021.

Seeds

 * 1 Rankings as of 19 July 2021.

Other entrants
The following players received a wildcard into the singles main draw:
 * 🇺🇸 Louisa Chirico
 * 🇺🇸 Fiona Crawley
 * 🇺🇸 Ellie Douglas
 * 🇷🇸 Katarina Jokić

The following players received entry using protected rankings:
 * 🇨🇦 Rebecca Marino
 * 🇹🇭 Peangtarn Plipuech
 * 🇨🇦 Carol Zhao

Withdrawals

 * Before the tournament
 * 🇺🇸 Hailey Baptiste → replaced by 🇺🇸 Emma Navarro
 * 🇩🇪 Mona Barthel → replaced by 🇺🇸 Robin Anderson
 * 🇪🇸 Aliona Bolsova → replaced by 🇺🇸 Maria Mateas
 * 🇫🇷 Clara Burel → replaced by 🇺🇦 Kateryna Bondarenko
 * 🇦🇺 Lizette Cabrera → replaced by 🇺🇸 Hanna Chang
 * 🇬🇧 Harriet Dart → replaced by 🇹🇭 Peangtarn Plipuech
 * 🇺🇸 Francesca Di Lorenzo → replaced by 🇰🇷 Han Na-lae
 * 🇺🇸 Caroline Dolehide → replaced by 🇺🇸 Usue Maitane Arconada
 * 🇵🇱 Magdalena Fręch → replaced by 🇺🇸 Catherine Harrison
 * 🇷🇺 Anastasia Gasanova → replaced by 🇺🇸 Sachia Vickery
 * 🇮🇹 Giulia Gatto-Monticone → replaced by 🇧🇷 Beatriz Haddad Maia
 * Leonie Küng → replaced by Liang En-shuo
 * 🇺🇸 Christina McHale → replaced by 🇺🇸 Allie Kiick
 * 🇪🇸 Nuria Párrizas Díaz → replaced by 🇺🇸 Whitney Osuigwe
 * 🇷🇺 Natalia Vikhlyantseva → replaced by Aldila Sutjiadi
 * 🇲🇽 Renata Zarazúa → replaced by 🇺🇸 Alexa Glatch

Seeds

 * 1 Rankings as of 19 July 2021.

Other entrants
The following pair received a wildcard into the doubles main draw:
 * 🇺🇸 Sophie Chang / 🇺🇸 Emma Navarro

Singles

 * 🇺🇸 Varvara Lepchenko def. 🇺🇸 Jamie Loeb 7–6(7–4), 4–6, 6–4

Doubles

 * Liang En-shuo / 🇨🇦 Rebecca Marino def. 🇳🇿 Erin Routliffe / Aldila Sutjiadi, 5–7, 7–5, [10–7]