2021 L'Open 35 de Saint-Malo

The 2021 L'Open 35 de Saint-Malo was a professional tennis tournament played on outdoor clay courts. It was the twenty-sixth edition of the tournament and its first as part of the 2021 edition of the WTA 125K series. It took place in Saint-Malo, France between 3 and 9 May 2021.

Seeds

 * 1 Rankings are as of 26 April 2021.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇫🇷 Clara Burel
 * 🇫🇷 Elsa Jacquemot
 * 🇫🇷 Diane Parry
 * 🇫🇷 Harmony Tan

The following players received entry from the qualifying draw:
 * 🇫🇷 Tessah Andrianjafitrimo
 * 🇧🇷 Luisa Stefani
 * Clara Tauson
 * 🇧🇬 Viktoriya Tomova

The following player received entry as a lucky loser:
 * 🇫🇷 Amandine Hesse

Withdrawals

 * Before the tournament
 * 🇪🇸 Paula Badosa → replaced by 🇧🇪 Greet Minnen
 * 🇷🇴 Irina-Camelia Begu → replaced by 🇪🇸 Aliona Bolsova
 * 🇷🇺 Anna Blinkova → replaced by 🇷🇺 Varvara Gracheva
 * 🇺🇸 Lauren Davis → replaced by 🇮🇹 Martina Trevisan
 * 🇰🇿 Zarina Diyas → replaced by 🇷🇺 Anna Kalinskaya
 * 🇯🇵 Misaki Doi → replaced by 🇸🇰 Anna Karolína Schmiedlová
 * 🇫🇷 Caroline Garcia → replaced by 🇧🇾 Aliaksandra Sasnovich
 * 🇮🇹 Camila Giorgi → replaced by 🇺🇦 Kateryna Kozlova
 * Polona Hercog → replaced by 🇫🇷 Océane Dodin
 * 🇯🇵 Nao Hibino → replaced by 🇫🇷 Amandine Hesse
 * 🇪🇪 Kaia Kanepi → replaced by 🇨🇿 Tereza Martincová
 * 🇲🇪 Danka Kovinić → replaced by 🇮🇹 Jasmine Paolini
 * 🇩🇪 Laura Siegemund → replaced by 🇨🇳 Wang Xiyu

Seeds

 * 1 Rankings as of April 26, 2021.

Singles

 * Viktorija Golubic def. 🇮🇹 Jasmine Paolini, 6–1, 6–3

Doubles

 * 🇺🇸 Kaitlyn Christian / 🇺🇸 Sabrina Santamaria def. 🇺🇸 Hayley Carter / 🇧🇷 Luisa Stefani, 7–6(7–4), 4–6, [10–5]