2021 Columbus Challenger – Women's doubles

This was the first edition of the women's event.

Wang Xinyu and Zheng Saisai won the title, defeating Dalila Jakupović and Nuria Párrizas Díaz in the final, 6–1, 6–1.

Seeds
All seeds received a bye into the quarterfinals, along with one other team. • # 🇺🇸 Ingrid Neel / 🇺🇸 Sabrina Santamaria (quarterfinals)

• # 🇳🇴 Ulrikke Eikeri / 🇫🇷 Elixane Lechemia (semifinals)

• # 🇺🇸 Jamie Loeb / 🇺🇸 Asia Muhammad (quarterfinals, withdrew)

• # Liang En-shuo / 🇨🇦 Rebecca Marino (semifinals)