2023 US Open – Girls' singles

Katherine Hui won the girls' singles title at the 2023 US Open, defeating Tereza Valentová in the final, 6–4, 6–4. Hui won the tournament without losing a set.

Alex Eala was the reigning champion, but chose not to participate.

Seeds
• 🇸🇰 Renáta Jamrichová (semifinals)

• 🇵🇪 Lucciana Pérez Alarcón (second round)

• 🇯🇵 Sayaka Ishii (third round)

• 🇯🇵 Sara Saito (quarterfinals)

• 🇯🇵 Mayu Crossley (withdrew)

• 🇯🇵 Ena Koike (quarterfinals)

• 🇺🇸 Kaitlin Quevedo (third round)

• 🇺🇸 Iva Jovic (first round)

• 🇨🇿 Tereza Valentová (final)

• 🇨🇿 Laura Samsonová (semifinals)

• Anastasiia Gureva (quarterfinals)

• 🇦🇺 Emerson Jones (first round)

• 🇨🇿 Alena Kovačková (second round)

• 🇷🇸 Teodora Kostović (second round)

• Rebecca Munk Mortensen (first round)

• 🇪🇸 Charo Esquiva Banuls (third round)

Seeds
• # 🇧🇯 Gloriana Nahum (first round)

• # 🇮🇱 Mika Buchnik (qualifying competition)

• # 🇳🇴 Emily Sartz-Lunde (first round)

• # 🇲🇦 Malak El Allami (first round)

• # 🇮🇹 Noemi Basiletti (qualified)

• # 🇮🇹 Emma Ottavia Ghirardato (first round)

• # 🇮🇹 Francesca Gandolfi (first round)

• # 🇦🇺 Roisin Gilheany (first round)

• # 🇮🇱 Liam Oved (qualifying competition)

• # 🇺🇸 Kaitlyn Rolls (qualifying competition)

• # 🇺🇸 Anya Murthy (qualifying competition)

• # 🇨🇦 Naomi Xu (qualifying competition)

• # 🇮🇹 Gaia Maduzzi (qualified)

• # 🇬🇧 Hephzibah Oluwadare (first round)

• # 🇮🇹 Greta Greco Lucchina (first round)

• # 🇺🇸 Piper Charney (first round)

Qualifiers
• # 🇬🇧 Mika Stojsavljevic

• # 🇺🇸 Jessica Bernales

• # 🇯🇵 Nanaka Sato

• # 🇺🇸 Shannon Lam

• # 🇮🇹 Noemi Basiletti

• # 🇺🇸 Annika Penickova

• # 🇺🇸 Olivia Center

• # 🇮🇹 Gaia Maduzzi

Lucky losers
• # 🇵🇱 Olivia Bergler

• # 🇺🇸 Thea Frodin