2010 US Open – Girls' doubles

Valeria Solovieva and Maryna Zanevska were the defending champions but did not enter the junior competition this year.

Tímea Babos and Sloane Stephens won the title, because their opponents An-Sophie Mestach and Silvia Njirić withdrew before the final match. This was their third Grand Slam girls' doubles title in the year after winning at the French Open and at the Wimbledon Championships. Babos has reached all four junior doubles finals in one single calendar year.

Seeds
• # 🇷🇺 Daria Gavrilova / 🇷🇺 Irina Khromacheva (semifinals)

• # 🇨🇿 Karolína Plíšková / 🇨🇿 Kristýna Plíšková (first round)

• # 🇭🇺 Tímea Babos / 🇺🇸 Sloane Stephens (champions)

• # 🇫🇷 Caroline Garcia / Monica Puig (first round)

• # 🇸🇰 Jana Čepelová / 🇸🇰 Chantal Škamlová (quarterfinals)

• # Verónica Cepede Royg / 🇷🇴 Cristina Dinu (second round)

• # 🇹🇳 Ons Jabeur / 🇷🇺 Yulia Putintseva (quarterfinals)

• # 🇨🇦 Eugenie Bouchard / 🇨🇦 Gabriela Dabrowski (second round)