1901 U.S. National Championships – Women's singles

Elisabeth Moore won the singles tennis title of the 1901 U.S. Women's National Singles Championship by defeating reigning champion Myrtle McAteer 6–4, 3–6, 7–5, 2–6, 6–2 in the challenge round. The draw included four past or present champions. Moore had won the right to challenge McAteer by defeating Marion Jones 4–6, 1–6, 9–7, 9–7, 6–3 in the final of the All Comers' competition. The event was played on outdoor grass courts and held at the Philadelphia Cricket Club in Wissahickon Heights, Chestnut Hill, Philadelphia from June 25 through June 29, 1901.