1907 U.S. National Championships – Women's singles

Evelyn Sears won the singles tennis title of the 1907 U.S. Women's National Singles Championship by defeating Carrie Neely 6–3, 6–2 in the final of the All Comers' tournament. Helen Homans was the reigning champion but did not defend her title in the Challenge Round. The event was played on outdoor grass courts and held at the Philadelphia Cricket Club in Wissahickon Heights, Chestnut Hill, Philadelphia from June 25 through July 2, 1907.