2015 Australian Open – Women's singles

Serena Williams defeated Maria Sharapova in the final, 6–3, 7–6(7–5) to win the women's singles tennis title at the 2015 Australian Open. It was her sixth Australian Open singles title and her 19th major singles title overall. Sharapova reached the final after being two match points down in the second round against Alexandra Panova. The final was a rematch of the 2007 final.

Li Na was the reigning champion, but she retired from professional tennis in September 2014.

All of the top four seeds (Williams, Sharapova, Simona Halep, and Petra Kvitová) were in contention for the world No. 1 ranking. Williams retained the top position by reaching the final.

Seeds
• 🇺🇸 Serena Williams (champion)

• 🇷🇺 Maria Sharapova (final)

• 🇷🇴 Simona Halep (quarterfinals)

• 🇨🇿 Petra Kvitová (third round)

• 🇷🇸 Ana Ivanovic (first round)

• 🇵🇱 Agnieszka Radwańska (fourth round)

• 🇨🇦 Eugenie Bouchard (quarterfinals)

• Caroline Wozniacki (second round)

• 🇩🇪 Angelique Kerber (first round)

• 🇷🇺 Ekaterina Makarova (semifinals)

• 🇸🇰 Dominika Cibulková (quarterfinals)

• 🇮🇹 Flavia Pennetta (first round)

• 🇩🇪 Andrea Petkovic (first round)

• 🇮🇹 Sara Errani (third round)

• 🇷🇸 Jelena Janković (first round)

• 🇨🇿 Lucie Šafářová (first round)

• 🇪🇸 Carla Suárez Navarro (first round)

• 🇺🇸 Venus Williams (quarterfinals)

• 🇫🇷 Alizé Cornet (third round)

• 🇦🇺 Samantha Stosur (second round)

• 🇨🇳 Peng Shuai (fourth round)

• 🇨🇿 Karolína Plíšková (third round)

• 🇷🇺 Anastasia Pavlyuchenkova (first round)

• 🇪🇸 Garbiñe Muguruza (fourth round)

• 🇨🇿 Barbora Záhlavová-Strýcová (third round)

• 🇺🇦 Elina Svitolina (third round)

• 🇷🇺 Svetlana Kuznetsova (first round)

• 🇩🇪 Sabine Lisicki (first round)

• 🇦🇺 Casey Dellacqua (second round)

• 🇺🇸 Varvara Lepchenko (third round)

• 🇰🇿 Zarina Diyas (third round)

• Belinda Bencic (first round)