2019 Australian Open – Men's singles

Novak Djokovic defeated Rafael Nadal in the final, 6–3, 6–2, 6–3 to win the men's singles tennis title at the 2019 Australian Open. It was his record-breaking seventh Australian Open title and 15th major title overall, surpassing Pete Sampras for third place on the all-time list. Djokovic and Nadal were both in contention for the world No. 1 singles ranking; Djokovic retained the top ranking by reaching the fourth round. Nadal was attempting to become the first man in the Open Era to achieve a double career Grand Slam, a feat he would achieve three years later.

Roger Federer was the two-time defending champion, but lost in the fourth round to Stefanos Tsitsipas. Tsitsipas became the first Greek player to reach the semifinals at a singles major, after becoming the first man representing Greece to win a main-draw singles match at the Australian Open.

This was the first Australian Open since 1982 to feature a final set tie-break. Upon reaching 6–6 in the fifth set, a match tie-break is played where the winner is the first to reach ten points and lead by two points. The first men's singles main-draw match to feature the ten-point tiebreak was the first-round match between Jérémy Chardy and Ugo Humbert.

Seeds
All seedings per ATP rankings. • 🇷🇸 Novak Djokovic (champion)

• 🇪🇸 Rafael Nadal (final)

• Roger Federer (fourth round)

• 🇩🇪 Alexander Zverev (fourth round)

•  Kevin Anderson (second round)

•  Marin Čilić (fourth round)

• 🇦🇹 Dominic Thiem (second round, retired)

• 🇯🇵 Kei Nishikori (quarterfinals, retired)

• 🇺🇸 John Isner (first round)

• 🇷🇺 Karen Khachanov (third round)

•  Borna Ćorić (fourth round)

• 🇮🇹 Fabio Fognini (third round)

• 🇬🇧 Kyle Edmund (first round)

•  Stefanos Tsitsipas (semifinals)

• 🇷🇺 Daniil Medvedev (fourth round)

• 🇨🇦 Milos Raonic (quarterfinals)

• 🇮🇹 Marco Cecchinato (first round)

• 🇦🇷 Diego Schwartzman (third round)

•  Nikoloz Basilashvili (third round)

• 🇧🇬 Grigor Dimitrov (fourth round)

• 🇧🇪 David Goffin (third round)

• 🇪🇸 Roberto Bautista Agut (quarterfinals)

• 🇪🇸 Pablo Carreño Busta (fourth round)

• 🇰🇷 Chung Hyeon (second round)

• 🇨🇦 Denis Shapovalov (third round)

• 🇪🇸 Fernando Verdasco (third round)

• 🇦🇺 Alex de Minaur (third round)

• 🇫🇷 Lucas Pouille (semifinals)

• 🇫🇷 Gilles Simon (second round)

• 🇫🇷 Gaël Monfils (second round)

• 🇺🇸 Steve Johnson (first round)

• 🇩🇪 Philipp Kohlschreiber (second round)

Championship match ratings
554 thousand on ESPN, in the USA