2011 Australian Open – Men's singles

Novak Djokovic defeated Andy Murray in the final, 6–4, 6–2, 6–3 to win the men's singles tennis title at the 2011 Australian Open. It was his second Australian Open title and second major title overall.

Roger Federer was the defending champion, but lost in the semifinals to Djokovic. With his quarterfinal win over Stanislas Wawrinka, Federer broke Jack Crawford's record for the most match wins at the Australian Open.

Rafael Nadal, the 2009 champion, was attempting to complete a non-calendar-year Grand Slam and to become the first man since Rod Laver in 1969 to hold all four major titles at once, having won the preceding French Open, Wimbledon and US Open in 2010, but lost in the quarterfinals to David Ferrer.

This was the last Australian Open appearance for 2001 finalist and former top 10 player Arnaud Clément.

Seeds
• 🇪🇸 Rafael Nadal (quarterfinals)

• Roger Federer (semifinals)

• 🇷🇸 Novak Djokovic (champion)

• 🇸🇪 Robin Söderling (fourth round)

• 🇬🇧 Andy Murray (final)

• 🇨🇿 Tomáš Berdych (quarterfinals)

• 🇪🇸 David Ferrer (semifinals)

• 🇺🇸 Andy Roddick (fourth round)

• 🇪🇸 Fernando Verdasco (fourth round)

• 🇷🇺 Mikhail Youzhny (third round)

• 🇦🇹 Jürgen Melzer (fourth round)

• 🇫🇷 Gaël Monfils (third round)

• 🇫🇷 Jo-Wilfried Tsonga (third round)

• 🇪🇸 Nicolás Almagro (fourth round)

•  Marin Čilić (fourth round)

• 🇺🇸 Mardy Fish (second round)

•  Ivan Ljubičić (third round)

• 🇺🇸 Sam Querrey (first round)

•  Stan Wawrinka (quarterfinals)

• 🇺🇸 John Isner (third round)

• 🇨🇾 Marcos Baghdatis (third round, retired due to a right finger injury)

• 🇫🇷 Michaël Llodra (second round)

• 🇷🇺 Nikolay Davydenko (first round)

•  Ernests Gulbis (first round)

• 🇪🇸 Albert Montañés (second round)

• 🇦🇷 Juan Mónaco (second round)

• 🇦🇷 David Nalbandian (second round, retired due to fatigue)

• 🇫🇷 Richard Gasquet (third round)

• 🇷🇸 Viktor Troicki (third round, retired due to stomach pain)

• 🇧🇷 Thomaz Bellucci (second round)

• 🇪🇸 Feliciano López (second round)

• 🇪🇸 Guillermo García-López (third round)