2011 Australian Open – Women's singles

Kim Clijsters defeated Li Na in the final, 3–6, 6–3, 6–3 to win the women's singles tennis title at the 2011 Australian Open. It was her first Australian Open title and her fourth and last major overall, as well as the last singles title of her career.

Li became the first Asian player to reach a singles major final, and would go on to win the French Open a few months later. This was the first major where Caroline Wozniacki competed as the world No. 1; she lost to Li in the semifinals, despite having a match point in the second set.

Serena Williams was the two-time reigning champion, but did not participate due to a long-term foot injury.

The fourth-round match between Svetlana Kuznetsova and Francesca Schiavone, which lasted 4 hours and 44 minutes, was the longest women's singles major match, with Schiavone winning in the third set, 16–14.

This marked the last major for two former world No. 1's: Justine Henin and Dinara Safina, who both retired due to injury (Henin's elbow and Safina's back).

Seeds
• Caroline Wozniacki (semifinals)

• 🇷🇺 Vera Zvonareva (semifinals)

• 🇧🇪 Kim Clijsters (champion)

• 🇺🇸 Venus Williams (third round, retired because of a hip injury)

• 🇦🇺 Samantha Stosur (third round)

• 🇮🇹 Francesca Schiavone (quarterfinals)

• 🇷🇸 Jelena Janković (second round)

• 🇧🇾 Victoria Azarenka (fourth round)

• 🇨🇳 Li Na (final)

• 🇮🇱 Shahar Pe'er (third round)

• 🇧🇪 Justine Henin (third round)

• 🇵🇱 Agnieszka Radwańska (quarterfinals)

• 🇷🇺 Nadia Petrova (third round)

• 🇷🇺 Maria Sharapova (fourth round)

• 🇫🇷 Marion Bartoli (second round)

• 🇷🇺 Anastasia Pavlyuchenkova (third round)

• 🇫🇷 Aravane Rezaï (first round)

• 🇷🇺 Maria Kirilenko (second round)

• 🇷🇸 Ana Ivanovic (first round)

• 🇪🇪 Kaia Kanepi (second round)

• 🇧🇪 Yanina Wickmayer (second round)

• 🇮🇹 Flavia Pennetta (fourth round)

• 🇷🇺 Svetlana Kuznetsova (fourth round)

• 🇷🇺 Alisa Kleybanova (second round)

• 🇨🇿 Petra Kvitová (quarterfinals)

• 🇪🇸 María José Martínez Sánchez (second round)

• 🇷🇴 Alexandra Dulgheru (first round)

• 🇸🇰 Daniela Hantuchová (first round)

• 🇸🇰 Dominika Cibulková (third round)

• 🇩🇪 Andrea Petkovic (quarterfinals)

• 🇨🇿 Lucie Šafářová (third round)

• 🇧🇬 Tsvetana Pironkova (second round)