2013 Australian Open – Mixed doubles

Bethanie Mattek-Sands and Horia Tecău were the defending champions, but lost in the first round to Lucie Hradecká and František Čermák.

Jarmila Gajdošová and Matthew Ebden won their first mixed doubles title, defeating Hradecká and František Čermák in the final, 6–3, 7–5. This would be Gajdošová's only Grand Slam title before her retirement in 2017.

Seeds
• # 🇺🇸 Lisa Raymond / 🇺🇸 Mike Bryan (withdrew)

• # 🇷🇺 Elena Vesnina / 🇮🇳 Leander Paes (second round)

• # 🇮🇳 Sania Mirza / 🇺🇸 Bob Bryan (quarterfinals)

• # 🇺🇸 Liezel Huber / 🇧🇾 Max Mirnyi (second round)

• # 🇷🇺 Nadia Petrova / 🇮🇳 Mahesh Bhupathi (quarterfinals)

• # 🇩🇪 Anna-Lena Grönefeld / 🇸🇪 Robert Lindstedt (withdrew)

• # 🇨🇿 Andrea Hlaváčková / 🇮🇹 Daniele Bracciali (second round)

• # 🇩🇪 Julia Görges / 🇨🇦 Daniel Nestor (withdrew)