2013 US Open – Mixed doubles

Ekaterina Makarova and Bruno Soares were the defending champions, but Makarova decided not to participate. Soares played with Anabel Medina Garrigues, but lost to Abigail Spears and Santiago González in the semifinals.

Andrea Hlaváčková and Max Mirnyi won the title, defeating Spears and González in the final, 7–6(7–5), 6–3.

Seeds
• # 🇩🇪 Anna-Lena Grönefeld / 🇦🇹 Alexander Peya (first round)

• # Katarina Srebotnik / 🇷🇸 Nenad Zimonjić (second round)

• # 🇩🇪 Julia Görges / 🇮🇳 Rohan Bopanna (first round)

• # 🇨🇿 Květa Peschke / 🇵🇱 Marcin Matkowski (quarterfinals)

• # 🇪🇸 Anabel Medina Garrigues / 🇧🇷 Bruno Soares (semifinals)

• # 🇺🇸 Lisa Raymond / Jean-Julien Rojer (second round)

• # 🇨🇿 Andrea Hlaváčková / 🇧🇾 Max Mirnyi (champions)

• # 🇺🇸 Liezel Huber / 🇧🇷 Marcelo Melo (quarterfinals)