2016 Australian Open – Mixed doubles

Martina Hingis and Leander Paes were the defending champions, but lost in the quarterfinals to Sania Mirza and Ivan Dodig.

Elena Vesnina and Bruno Soares won the title, defeating CoCo Vandeweghe and Horia Tecău in the final, 6–4, 4–6, [10–5].

Seeds
• # 🇮🇳 Sania Mirza / Ivan Dodig (semifinals)

• # 🇺🇸 Bethanie Mattek-Sands / 🇺🇸 Bob Bryan (quarterfinals)

• # Chan Yung-jan  / 🇮🇳 Rohan Bopanna (quarterfinals)

• # Katarina Srebotnik  / 🇬🇧 Jamie Murray (quarterfinals)

• # 🇷🇺 Elena Vesnina / 🇧🇷 Bruno Soares (champions)

• # 🇨🇿 Lucie Hradecká / 🇵🇱 Marcin Matkowski (first round)

• # 🇺🇸 Raquel Atawo / Raven Klaasen (first round)

• # Chan Hao-ching  / 🇧🇾 Max Mirnyi (first round)