2019 Abierto Mexicano Telcel – Men's singles

Nick Kyrgios defeated Alexander Zverev in the final, 6–3, 6–4 to win the men's singles tennis title at the 2019 Mexican Open. Kyrgios saved three match points en route to the title, in his second-round match against Rafael Nadal.

Juan Martín del Potro was the reigning champion, but withdrew due to injury before the tournament began.

Seeds
• #🇪🇸 Rafael Nadal (second round)

• #🇩🇪 Alexander Zverev (final)

• #🇺🇸 John Isner (semifinals)

• #🇦🇷 Diego Schwartzman (second round)

• #🇦🇺 Alex de Minaur (quarterfinals)

• #🇺🇸 Frances Tiafoe (second round)

• #🇺🇸 Steve Johnson (second round)

• #🇦🇺 John Millman (quarterfinals)

Seeds
• # 🇦🇺 Jordan Thompson (moved to main draw)

• # 🇦🇺 Bernard Tomic (qualifying competition, withdrew)

• # 🇺🇸 Ryan Harrison (qualified)

• # 🇪🇸 Guillermo García López (qualifying competition, lucky loser)

• # 🇪🇸 Marcel Granollers (qualified)

• # 🇦🇺 Alexei Popyrin (qualified)

• # 🇪🇸 Adrián Menéndez Maceiras (qualifying competition)

• # 🇮🇹 Federico Gaio (qualified)

Qualifiers
• # 🇮🇹 Federico Gaio

• # 🇦🇺 Alexei Popyrin

• # 🇺🇸 Ryan Harrison

• # 🇪🇸 Marcel Granollers

Lucky loser
• # 🇪🇸 Guillermo García López