2021 JSM Challenger of Champaign–Urbana

The 2021 JSM Challenger of Champaign–Urbana was a professional tennis tournament played on hard courts. It was the 25th edition of the tournament which was part of the 2021 ATP Challenger Tour. It took place in Champaign, Illinois, United States between November 15 and November 21, 2021.

Seeds

 * 1 Rankings are as of November 8, 2021.

Other entrants
The following players received wildcards into the singles main draw:
 * 🇺🇸 Ezekiel Clark
 * 🇺🇸 Vasil Kirkov
 * 🇺🇸 Aleksandar Kovacevic

The following players received entry from the qualifying draw:
 * Gijs Brouwer
 * 🇮🇳 Arjun Kadhe
 * 🇺🇸 Ben Shelton
 * 🇺🇸 Keegan Smith

Singles

 * 🇺🇸 Stefan Kozlov def. 🇦🇺 Aleksandar Vukic 5–7, 6–3, 6–4.

Doubles

 * 🇺🇸 Nathaniel Lammons / 🇺🇸 Jackson Withrow def. Treat Huey / 🇺🇸 Max Schnur 6–4, 3–6, [10–6]