2012 BNP Paribas Open – Men's singles

Roger Federer defeated John Isner in the final, 7–6(9–7), 6–3 to win the men's singles tennis title at the 2012 Indian Wells Masters. It was his record fourth Indian Wells title.

Novak Djokovic was the defending champion, but lost to Isner in the semifinals.

Seeds
All seeds received a bye into the second round. • # 🇷🇸 Novak Djokovic (semifinals)

• # 🇪🇸 Rafael Nadal (semifinals)

• # Roger Federer (champion)

• # Andy Murray (second round)

• # 🇪🇸 David Ferrer (third round)

• # 🇫🇷 Jo-Wilfried Tsonga (fourth round)

• # 🇨🇿 Tomáš Berdych (fourth round)

• # 🇺🇸 Mardy Fish (third round)

• # 🇦🇷 Juan Martín del Potro (quarterfinals)

• # 🇷🇸 Janko Tipsarević (third round)

• # 🇺🇸 John Isner (final)

• # 🇪🇸 Nicolás Almagro (quarterfinals)

• # 🇫🇷 Gilles Simon (quarterfinals)

• # 🇫🇷 Gaël Monfils (withdrew because of gastroenteritis)

• # 🇪🇸 Feliciano López (second round)

• # 🇫🇷 Richard Gasquet (second round)

• # 🇯🇵 Kei Nishikori (second round)

• # 🇩🇪 Florian Mayer (second round)

• # 🇪🇸 Fernando Verdasco (third round)

• # 🇦🇹 Jürgen Melzer (second round)

• # 🇺🇦 Alexandr Dolgopolov (fourth round)

• # 🇦🇷 Juan Mónaco (third round)

• # Stanislas Wawrinka (third round)

• # Marin Čilić (second round)

• # 🇷🇸 Viktor Troicki (second round)

• # 🇪🇸 Marcel Granollers (third round)

• # 🇨🇦 Milos Raonic (third round)

• # 🇨🇿 Radek Štěpánek (third round)

• # Kevin Anderson (third round)

• # 🇺🇸 Andy Roddick (third round)

• # 🇦🇷 Juan Ignacio Chela (second round)

• # 🇫🇷 Julien Benneteau (second round)

Seeds
• # Frederico Gil (qualifying competition, lucky loser)

• # 🇩🇪 Tobias Kamke (qualifying competition, lucky loser)

• # 🇦🇺 Matthew Ebden (qualified)

• # 🇮🇹 Paolo Lorenzi (qualified)

• # 🇧🇷 João Souza (first round)

• # 🇷🇺 Igor Andreev (first round)

• # 🇹🇷 Marsel İlhan (first round)

• # 🇩🇪 Björn Phau (qualifying competition, lucky loser)

• # 🇨🇦 Vasek Pospisil (qualified)

• # 🇺🇸 Bobby Reynolds (qualified)

• # Rik de Voest (qualified)

• # 🇧🇷 Ricardo Mello (first round)

• # 🇪🇪 Jürgen Zopp (qualifying competition)

• # Thomas Schoorel (qualifying competition)

• # 🇺🇸 Michael Russell (qualifying competition)

• # 🇦🇺 Marinko Matosevic (qualified)

• # Izak van der Merwe (qualifying competition)

• # 🇰🇿 Andrey Golubev (qualified)

• # 🇧🇷 Júlio Silva (first round)

• # 🇪🇸 Arnau Brugués Davi (first round)

• # 🇺🇸 Rajeev Ram (qualifying competition)

• # Marco Chiudinelli (first round)

• # 🇬🇧 James Ward (first round)

• # 🇧🇪 Ruben Bemelmans (qualified)

Qualifiers
• # 🇧🇪 Ruben Bemelmans

• # 🇧🇦 Amer Delić

• # 🇦🇺 Matthew Ebden

• # 🇮🇹 Paolo Lorenzi

• # 🇺🇦 Sergei Bubka

• # 🇺🇸 Tim Smyczek

• # 🇺🇸 Rhyne Williams

• # 🇰🇿 Andrey Golubev

• # 🇨🇦 Vasek Pospisil

• # 🇺🇸 Bobby Reynolds

• # Rik de Voest

• # 🇦🇺 Marinko Matosevic

Lucky losers

 * 1)  Frederico Gil
 * 2) 🇩🇪 Tobias Kamke
 * 3) 🇩🇪 Björn Phau