2012 Italian Open – Men's doubles

John Isner and Sam Querrey were the defending champions but lost in the first round to Jürgen Melzer and Philipp Petzschner. Marcel Granollers and Marc López won the title defeating Łukasz Kubot and Janko Tipsarević 6–3, 6–2 in the final.

Seeds
All seeds receive a bye into the second round. • # 🇧🇾 Max Mirnyi / 🇨🇦 Daniel Nestor (quarterfinals)

• # 🇺🇸 Bob Bryan / 🇺🇸 Mike Bryan (quarterfinals)

• # 🇫🇷 Michaël Llodra / 🇷🇸 Nenad Zimonjić (quarterfinals)

• # 🇸🇪 Robert Lindstedt / 🇷🇴 Horia Tecău (semifinals)

• # 🇮🇳 Leander Paes / 🇨🇿 Radek Štěpánek (second round)

• # 🇵🇱 Mariusz Fyrstenberg / 🇵🇱 Marcin Matkowski (quarterfinals)

• # 🇮🇳 Mahesh Bhupathi / 🇮🇳 Rohan Bopanna (semifinals)

• # 🇦🇹 Alexander Peya / 🇵🇰 Aisam-ul-Haq Qureshi (second round)