2012 French Open – Men's singles

Two-time defending champion Rafael Nadal defeated Novak Djokovic in the final, 6–4, 6–3, 2–6, 7–5 to win the men's singles tennis title at the 2012 French Open. It was his record-breaking seventh French Open title and eleventh major title overall, surpassing Björn Borg's Open Era record of six French Open men's singles titles and equaling Pete Sampras' Wimbledon record for men's singles titles at one major in the Open Era. He also equaled Chris Evert's all-gender record for the most French Open singles titles overall.

Djokovic was attempting to complete a non-calendar-year Grand Slam and to become the first man since Rod Laver in 1969 to hold all four major titles at once, having won the previous year's Wimbledon and US Open titles as well as this year's Australian Open (all won over Nadal in the final). It was Djokovic's fourth consecutive loss to Nadal at Roland Garros, but the first time Djokovic won a set against Nadal at the tournament.

Roger Federer was attempting to become the first man in the Open Era and the third man ever to achieve a double career Grand Slam, but he lost to Djokovic in the semifinals in a rematch of the previous year's semifinal.

Due to rain, the final was suspended to Monday, 11 June 2012 at 13:00 local time, after the score on Sunday was 6–4, 6–3, 2–6, 1–2 with Djokovic serving, after 3 hours of play of the 3:49 total length.

This was the last major appearance for 2001 Australian Open finalist and former world No. 10 Arnaud Clement, and the last French Open appearance for 2003 champion and former world No. 1 Juan Carlos Ferrero and for former world No. 1 Andy Roddick.

Seeds
• 🇷🇸 Novak Djokovic (final)

• 🇪🇸 Rafael Nadal (champion)

• Roger Federer (semifinals)

• 🇬🇧 Andy Murray (quarterfinals)

• 🇫🇷 Jo-Wilfried Tsonga (quarterfinals)

• 🇪🇸 David Ferrer (semifinals)

• 🇨🇿 Tomáš Berdych (fourth round)

• 🇷🇸 Janko Tipsarević (fourth round)

• 🇦🇷 Juan Martín del Potro (quarterfinals)

• 🇺🇸 John Isner (second round)

• 🇫🇷 Gilles Simon (third round)

• 🇪🇸 Nicolás Almagro (quarterfinals)

• 🇦🇷 Juan Mónaco (fourth round)

• 🇪🇸 Fernando Verdasco (third round)

• 🇪🇸 Feliciano López (first round, retired because of a left oblique injury)

• 🇺🇦 Alexandr Dolgopolov (first round)

• 🇫🇷 Richard Gasquet (fourth round)

•  Stan Wawrinka (fourth round)

• 🇨🇦 Milos Raonic (third round)

• 🇪🇸 Marcel Granollers (fourth round)

•  Marin Čilić (third round)

• 🇮🇹 Andreas Seppi (fourth round)

• 🇨🇿 Radek Štěpánek (first round)

• 🇩🇪 Philipp Kohlschreiber (second round)

• 🇦🇺 Bernard Tomic (second round)

• 🇺🇸 Andy Roddick (first round)

• 🇷🇺 Mikhail Youzhny (third round)

• 🇷🇸 Viktor Troicki (second round)

• 🇫🇷 Julien Benneteau (third round)

• 🇦🇹 Jürgen Melzer (first round)

•  Kevin Anderson (third round)

• 🇩🇪 Florian Mayer (second round)