2012 Valencia Open 500 – Singles

Marcel Granollers was the defending champion, but lost to Alexandr Dolgopolov in the quarterfinals.

David Ferrer won the title, defeating Dolgopolov in the final, 6–1, 3–6, 6–4.

Former world No. 1 Juan Carlos Ferrero played his last match at the tournament losing to 6th seed Nicolás Almagro in the first round in straight sets.

Seeds
• # 🇪🇸 David Ferrer (champion)

• # 🇫🇷 Jo-Wilfried Tsonga (first round, retired because of a back injury)

• # 🇷🇸 Janko Tipsarević (first round, retired because of a right shoulder injury)

• # 🇦🇷 Juan Mónaco (first round)

• # 🇺🇸 John Isner (second round)

• # 🇪🇸 Nicolás Almagro (quarterfinals)

• # Marin Čilić (quarterfinals)

• # 🇨🇦 Milos Raonic (first round)

Seeds
• # 🇪🇸 Daniel Gimeno Traver (qualifying competition)

• # 🇪🇸 Roberto Bautista Agut (qualifying competition)

• # 🇮🇹 Flavio Cipolla (first round)

• # 🇩🇪 Philipp Petzschner (qualifying competition)

• # 🇺🇸 Rajeev Ram (qualified)

• # 🇱🇹 Ričardas Berankis (first round)

• # 🇧🇪 Olivier Rochus (qualified)

• # Ivan Dodig (qualified)

Qualifiers
• # 🇨🇿 Jan Hájek

• # 🇧🇪 Olivier Rochus

• # Ivan Dodig

• # 🇺🇸 Rajeev Ram