2022 Dow Tennis Classic – Singles

Madison Brengle was the defending champion, but lost in the second round to Sofia Kenin.

Caty McNally won the title, defeating Anna-Lena Friedsam in the final, 6–3, 6–2.

Seeds
• # 🇨🇳 Zhang Shuai (first round)

• # 🇺🇸 Madison Brengle (second round)

• # 🇨🇳 Zhu Lin (second round)

• # 🇨🇳 Yuan Yue (withdrew)

• # 🇨🇴 Camila Osorio (quarterfinals)

• # Varvara Gracheva (first round)

• # 🇺🇸 Caty McNally (champion)

• # 🇯🇵 Moyuka Uchijima (first round)

Seeds
• # 🇺🇸 Kayla Day (qualified)

• # Diana Shnaider (qualifying competition)

• # 🇺🇸 Elvina Kalieva (qualified)

• # 🇺🇸 Sophie Chang (qualifying competition, lucky loser)

• # 🇨🇦 Katherine Sebov (qualified)

• # 🇺🇸 Jamie Loeb (qualifying competition)

• # 🇺🇸 Francesca Di Lorenzo (qualifying competition)

• # 🇺🇸 Robin Montgomery (qualified)

Qualifiers
• # 🇺🇸 Kayla Day

• # 🇺🇸 Robin Montgomery

• # 🇺🇸 Elvina Kalieva

• # 🇨🇦 Katherine Sebov

Lucky loser
• # 🇺🇸 Sophie Chang