2010 UNICEF Open – Women's singles

Tamarine Tanasugarn was the defending champion, but she lost against Anastasia Rodionova in the first round. First-seeded Justine Henin won the final 3–6, 6–3, 6–4 against Andrea Petkovic.

Seeds
• # 🇧🇪 Justine Henin (champion)

• # 🇷🇺 Dinara Safina (first round)

• # 🇷🇺 Maria Kirilenko (second round, retired due to abdominal injury)

• # 🇰🇿 Yaroslava Shvedova (quarterfinals)

• # 🇷🇴 Alexandra Dulgheru (semifinals)

• # 🇮🇹 Sara Errani (first round)

• # 🇩🇪 Andrea Petkovic (final)

• # 🇪🇸 Anabel Medina Garrigues (first round)