2009 US Open – Mixed doubles

Cara Black and Leander Paes were the defending champions, but were defeated by Carly Gullickson and Travis Parrott in the final 2–6, 4–6.

Seeds
• # 🇺🇸 Liezel Huber / 🇮🇳 Mahesh Bhupathi (semifinals)

• # Cara Black / 🇮🇳 Leander Paes (final)

• # 🇺🇸 Lisa Raymond / 🇵🇱 Marcin Matkowski (quarterfinals)

• # 🇩🇪 Anna-Lena Grönefeld / Mark Knowles (second round)

• # Hsieh Su-wei /  Kevin Ullyett (semifinals)

• # 🇷🇺 Nadia Petrova / 🇧🇾 Max Mirnyi (first round)

• # 🇦🇺 Rennae Stubbs / 🇸🇪 Robert Lindstedt (quarterfinals)

• # 🇺🇸 Bethanie Mattek-Sands / 🇷🇸 Nenad Zimonjić (quarterfinals)