2012 BGL Luxembourg Open – Singles

Victoria Azarenka was the defending champion but decided not to participate. Venus Williams won the title, defeating Monica Niculescu 6–2 6–3.

Seeds
• # 🇮🇹 Roberta Vinci (quarterfinals)

• # 🇩🇪 Julia Görges (second round)

• # 🇷🇸 Jelena Janković (second round)

• # 🇧🇪 Yanina Wickmayer (withdrew due to a knee injury)

• # 🇩🇪 Sabine Lisicki (first round)

• # 🇷🇴 Sorana Cîrstea (second round)

• # 🇦🇹 Tamira Paszek (first round)

• # 🇪🇸 Carla Suárez Navarro (first round)

• # 🇩🇪 Mona Barthel (second round)

Seeds
• # 🇷🇴 Irina-Camelia Begu (second round, retired)

• # 🇨🇿 Andrea Hlaváčková (second round)

• # 🇪🇸 Lara Arruabarrena Vecino (second round)

• # 🇬🇧 Anne Keothavong (qualifying competition, lucky loser)

• # 🇪🇸 Garbiñe Muguruza (qualified)

• # 🇩🇪 Tatjana Malek (qualified)

• # 🇩🇪 Annika Beck (qualified)

• # 🇷🇺 Vera Dushevina (qualified)

Qualifiers
• # 🇪🇸 Garbiñe Muguruza

• # 🇩🇪 Annika Beck

• # 🇩🇪 Tatjana Malek

• # 🇷🇺 Vera Dushevina

Lucky loser

 * 1) 🇬🇧 Anne Keothavong