2012 Barcelona Ladies Open – Singles

Roberta Vinci was the defending champion, but lost in the second round to Simona Halep 6–1, 6–3. Sara Errani won the tournament, beating Dominika Cibulková 6–2, 6–2 in the final.

Seeds
• # 🇮🇹 Francesca Schiavone (first round)

• # 🇩🇪 Julia Görges (quarterfinals)

• # 🇸🇰 Dominika Cibulková (final)

• # 🇮🇹 Roberta Vinci (second round)

• # 🇮🇹 Flavia Pennetta (second round)

• # 🇨🇿 Petra Cetkovská (second round)

• # 🇮🇹 Sara Errani (champion)

• # 🇸🇮 Polona Hercog (first round, retired)

Seeds
• # Arantxa Rus (first round)

• # 🇮🇹 Karin Knapp (first round)

• # 🇫🇷 Aravane Rezaï (qualified)

• # 🇪🇸 Estrella Cabeza Candela (qualifying competition, lucky loser)

• # 🇷🇺 Anastasia Pivovarova (first round)

• # 🇸🇮 Petra Rampre (qualifying competition)

• # 🇷🇺 Ekaterina Ivanova (second round)

• # 🇮🇹 Maria Elena Camerin (qualifying competition)

Qualifiers
• # 🇮🇹 Annalisa Bona

• # 🇺🇦 Yuliya Beygelzimer

• # 🇫🇷 Aravane Rezaï

• # 🇫🇷 Laura Thorpe