2012 Internationaux de Strasbourg – Singles

Andrea Petkovic was the defending champion, but did not participate because of an ankle injury.

Francesca Schiavone won the title, defeating Alizé Cornet in the final 6–4, 6–4.

Seeds
• # 🇩🇪 Sabine Lisicki (first round)

• # 🇮🇹 Francesca Schiavone (champion)

• # 🇷🇺 Maria Kirilenko (first round, retired)

• # 🇪🇸 Anabel Medina Garrigues (quarterfinals)

• # 🇩🇪 Mona Barthel (first round)

• # 🇳🇿 Marina Erakovic (first round)

• # 🇨🇿 Klára Zakopalová (withdrew)

• # 🇦🇹 Tamira Paszek (second round)

• # 🇨🇦 Aleksandra Wozniak (first round)

Seeds
• # 🇪🇸 María José Martínez Sánchez (qualifying competition, lucky loser)

• # 🇷🇺 Alexandra Panova (qualified)

• # 🇱🇺 Mandy Minella (qualifying competition, lucky loser)

• # 🇺🇸 Jamie Hampton (second round)

• # 🇪🇸 Laura Pous Tió (first round)

• # 🇨🇦 Stéphanie Dubois (qualifying competition)

• # Chang Kai-chen (first round)

• # Mirjana Lučić (qualified)

Qualifiers
• # Mirjana Lučić

• # 🇷🇺 Alexandra Panova

• # 🇺🇸 Lauren Davis

• # Anastasija Sevastova

Lucky loser

 * 1) 🇪🇸 María José Martínez Sánchez
 * 2) 🇱🇺 Mandy Minella