2012 Monterrey Open – Singles

Anastasia Pavlyuchenkova is the defending champion, but decided to participate at the Dubai Tennis Championships instead.

Tímea Babos won her first WTA title after defeating Alexandra Cadanțu 6–4, 6–4 in the final.

Seeds
• # 🇮🇹 Roberta Vinci (second round)

• # 🇮🇹 Sara Errani (semifinals)

• # 🇷🇴 Sorana Cîrstea (second round)

• # 🇷🇴 Alexandra Dulgheru (first round)

• # 🇦🇷 Gisela Dulko (first round)

• # 🇭🇺 Gréta Arn (semifinals)

• # 🇫🇷 Mathilde Johansson (first round)

• # 🇪🇸 Lourdes Domínguez Lino (quarterfinals)

Seeds
• # 🇰🇿 Sesil Karatantcheva (qualified)

• # 🇪🇸 Estrella Cabeza Candela (second round)

• # Petra Rampre (first round)

• # 🇦🇷 Florencia Molinero (first round)

• # Monica Puig (qualified)

• # 🇨🇴 Mariana Duque-Mariño (first round)

• # 🇨🇦 Sharon Fichman (second round)

• # 🇺🇦 Mariya Koryttseva (first round)

Qualifiers
• # 🇰🇿 Sesil Karatantcheva

• # Maria Abramović

• # 🇭🇺 Katalin Marosi

• # Monica Puig