2012 Tashkent Open – Singles

Ksenia Pervak was the defending champion, but decided not to participate.

Irina-Camelia Begu won the title, defeating Donna Vekić in the final, 6–4, 6–4.

Seeds
• # 🇷🇴 Monica Niculescu (first round)

• # 🇵🇱 Urszula Radwańska (semifinals)

• # 🇫🇷 Alizé Cornet (second round)

• # 🇸🇰 Magdaléna Rybáriková (first round)

• # 🇷🇴 Alexandra Cadanțu (quarterfinals)

• # 🇷🇸 Bojana Jovanovski (quarterfinals)

• # 🇷🇺 Alexandra Panova (quarterfinals)

• # 🇰🇿 Galina Voskoboeva (quarterfinals)

Seeds
• # 🇷🇺 Olga Puchkova (second round)

• # 🇷🇺 Alla Kudryavtseva (second round)

• # Bibiane Schoofs (second round)

• # Monica Puig (qualifying competition, lucky loser)

• # 🇷🇺 Marta Sirotkina (qualifying competition)

• # 🇹🇭 Noppawan Lertcheewakarn (first round)

• # 🇹🇷 Çağla Büyükakçay (qualifying competition)

• # 🇷🇺 Ekaterina Bychkova (qualified)

Qualifiers
• # 🇷🇺 Ekaterina Bychkova

• # 🇷🇺 Anna Chakvetadze

• # 🇷🇸 Vesna Dolonc

• # Donna Vekić

Lucky loser

 * 1)  Monica Puig