2012 Internazionali Femminili di Palermo – Singles

Anabel Medina Garrigues was the defending champion, but lost to Maria Elena Camerin in the first round.

Top seed Sara Errani won the title by beating Barbora Záhlavová-Strýcová 6–1, 6–3 in the final. She did not drop a set the entire tournament.

Seeds
• # 🇮🇹 Sara Errani (champion)

• # 🇮🇹 Roberta Vinci (second round)

• # 🇩🇪 Julia Görges (quarterfinals)

• # 🇪🇸 Anabel Medina Garrigues (first round)

• # 🇪🇸 Carla Suárez Navarro (quarterfinals)

• # Polona Hercog (first round)

• # 🇫🇷 Alizé Cornet (second round)

• # 🇨🇿 Barbora Záhlavová-Strýcová (final)

Seeds
• # 🇪🇸 Estrella Cabeza Candela (qualified)

• # 🇧🇬 Dia Evtimova (qualified)

• # 🇷🇺 Olga Puchkova (second round)

• # 🇧🇪 Tamaryn Hendler (first round)

• # 🇸🇮 Petra Rampre (first round)

• # 🇷🇴 Mădălina Gojnea (second round)

• # 🇦🇺 Sacha Jones (qualifying competition, lucky loser)

• # Tereza Mrdeža (qualifying competition)

Qualifiers
• # 🇪🇸 Estrella Cabeza Candela

• # 🇧🇬 Dia Evtimova

• # 🇭🇺 Katalin Marosi

• # 🇺🇦 Valentyna Ivakhnenko

Lucky losers

 * 🇦🇺 Sacha Jones