2012 Bank of the West Classic – Singles

Serena Williams was the defending champion, and successfully defended her title, defeating lucky loser CoCo Vandeweghe in the final, 7–5, 6–3. It was the first all-American final on the WTA Tour since the 2009 WTA Tour Championships, and the first on American soil since Los Angeles in 2004.

Seeds
The top four seeds received a bye into the second round. • # 🇺🇸 Serena Williams (champion)

• # 🇫🇷 Marion Bartoli (quarterfinals)

• # 🇸🇰 Dominika Cibulková (quarterfinals)

• # 🇷🇸 Jelena Janković (second round)

• # 🇧🇪 Yanina Wickmayer (semifinals)

• # Chanelle Scheepers (quarterfinals)

• # Petra Martić (withdrew)

• # 🇳🇿 Marina Erakovic (second round)

• # 🇷🇴 Sorana Cîrstea (semifinals)

Seeds
• # 🇰🇿 Sesil Karatantcheva (first round)

• # 🇺🇸 CoCo Vandeweghe (qualifying competition, lucky loser)

• # 🇯🇵 Erika Sema (qualified)

• # 🇺🇸 Alexa Glatch (qualifying competition, lucky loser)

• # 🇹🇭 Noppawan Lertcheewakarn (qualified)

• # Chan Yung-jan (first round)

• # 🇺🇸 Grace Min (qualified)

• # 🇨🇳 Zheng Saisai (qualifying competition, lucky loser)

Qualifiers
• # 🇺🇸 Grace Min

• # 🇹🇭 Noppawan Lertcheewakarn

• # 🇯🇵 Erika Sema

• # 🇸🇰 Jana Juricová

Lucky losers

 * 1) 🇺🇸 Alexa Glatch
 * 2) 🇺🇸 CoCo Vandeweghe
 * 3) 🇨🇳 Zheng Saisai