2012 Texas Tennis Open – Singles

Sabine Lisicki was the defending champion, but withdrew because of a left abdominal sprain. Roberta Vinci defeated Jelena Janković 7–5, 6–3 in the final to win the tournament.

Seeds
• # 🇩🇪 Angelique Kerber (withdrew because of a left shoulder injury)

• # 🇷🇸 Jelena Janković (final)

• # 🇮🇹 Roberta Vinci (champion)

• # 🇧🇪 Yanina Wickmayer (second round)

• # 🇨🇿 Klára Zakopalová (first round)

• # 🇨🇳 Peng Shuai (quarterfinals, retired because of a right shoulder injury)

• # Chanelle Scheepers (quarterfinals)

• # 🇷🇴 Sorana Cîrstea (quarterfinals)

Seeds
• # 🇭🇺 Melinda Czink (qualifying competition)

• # 🇫🇷 Pauline Parmentier (qualified)

• # Mirjana Lučić (qualified)

• # 🇦🇺 Casey Dellacqua (qualified)

• # 🇨🇦 Eugenie Bouchard (qualified)

• # 🇺🇸 Jennifer Elie (first round)

• # 🇨🇦 Gabriela Dabrowski (qualifying competition)

• # 🇬🇧 Emily Webley-Smith (qualifying competition, lucky loser)

Qualifiers
• # 🇨🇦 Eugenie Bouchard

• # 🇫🇷 Pauline Parmentier

• # Mirjana Lučić

• # 🇦🇺 Casey Dellacqua

Lucky loser

 * 1) 🇬🇧 Emily Webley-Smith