2012 Brussels Open – Singles

Caroline Wozniacki was the defending champion, but she chose not to participate. Agnieszka Radwańska won the title, defeating Simona Halep 7–5, 6–0 in the final.

Seeds
• # 🇵🇱 Agnieszka Radwańska (champion)

• # 🇫🇷 Marion Bartoli (second round)

• # 🇩🇪 Angelique Kerber (withdrew)

• # 🇸🇰 Dominika Cibulková (quarterfinals)

• # 🇮🇹 Roberta Vinci (withdrew)

• # 🇷🇸 Jelena Janković (first round)

• # 🇨🇳 Peng Shuai (first round)

• # 🇪🇪 Kaia Kanepi (semifinals)

• # 🇷🇺 Anastasia Pavlyuchenkova (first round)

• # 🇷🇺 Nadia Petrova (second round)

Seeds
• # 🇵🇱 Urszula Radwańska (qualified)

• # Arantxa Rus (qualified)

• # 🇺🇸 Irina Falconi (qualified)

• # 🇦🇺 Anastasia Rodionova (second round)

• # 🇺🇦 Lesia Tsurenko (qualifying round, lucky loser)

• # 🇷🇸 Bojana Jovanovski (qualifying round, lucky loser)

• # 🇦🇺 Olivia Rogowska (second round)

• # 🇦🇷 Paula Ormaechea (qualifying round)

Qualifiers
• # 🇵🇱 Urszula Radwańska

• # Arantxa Rus

• # 🇺🇸 Irina Falconi

• # 🇮🇳 Sania Mirza

Lucky losers

 * 1) 🇺🇦 Lesia Tsurenko
 * 2) 🇷🇸 Bojana Jovanovski