2008 French Open – Men's singles

Three-time defending champion Rafael Nadal defeated Roger Federer in a rematch of the two previous years' finals, 6–1, 6–3, 6–0 to win the men's singles tennis title at the 2008 French Open. It was his fourth French Open title and his fourth major title overall. This marks Federer's worst loss at a major in his entire career. It also marked the third consecutive year that Nadal defeated Federer in the French Open final, and the fourth consecutive year that Nadal defeated Federer at Roland Garros (extending back to their 2005 semifinal encounter). On all four occasions that Nadal won the French Open, he defeated Federer while the latter was the world No. 1 player. Nadal won the title without losing a set, becoming the third man in the Open Era after Ilie Năstase and Björn Borg to do so. He would later replicate this feat in 2010, 2017, and 2020. Federer was attempting to complete the career Grand Slam; he would achieve the feat the following year.

This tournament marked the final professional appearance of former world No. 1 and three-time French Open champion Gustavo Kuerten; he lost to Paul-Henri Mathieu in the first round. It was also the last major for 2004 French Open finalist and former world No. 3 Guillermo Coria, who lost in the first round to Tommy Robredo.

Seeds
• Roger Federer (final)

• 🇪🇸 Rafael Nadal (champion)

• 🇷🇸 Novak Djokovic (semifinals)

• 🇷🇺 Nikolay Davydenko (third round)

• 🇪🇸 David Ferrer (quarterfinals)

• 🇦🇷 David Nalbandian (second round)

• 🇺🇸 James Blake (second round)

• 🇫🇷 Richard Gasquet (withdrew due to a knee injury)

• Stan Wawrinka (third round)

• 🇬🇧 Andy Murray (third round)

• 🇨🇿 Tomáš Berdych (second round)

• 🇪🇸 Tommy Robredo (third round)

• 🇦🇷 Juan Mónaco (first round)

• 🇫🇷 Jo-Wilfried Tsonga (withdrew due to a knee injury)

• 🇷🇺 Mikhail Youzhny (third round)

• 🇪🇸 Carlos Moyá (first round)

• 🇨🇾 Marcos Baghdatis (first round)

• 🇫🇷 Paul-Henri Mathieu (fourth round)

• 🇪🇸 Nicolás Almagro (quarterfinals)

•  Ivo Karlović (first round)

• 🇨🇿 Radek Štěpánek (fourth round)

• 🇪🇸 Fernando Verdasco (fourth round)

• 🇪🇸 Juan Carlos Ferrero (first round, retired)

•  Fernando González (quarterfinals)

• 🇦🇺 Lleyton Hewitt (third round)

• 🇫🇮 Jarkko Nieminen (third round)

• 🇷🇺 Igor Andreev (second round)

•  Ivan Ljubičić (fourth round)

• 🇦🇷 Guillermo Cañas (first round)

• 🇷🇺 Dmitry Tursunov (third round)

• 🇮🇹 Andreas Seppi (first round)

• 🇷🇸 Janko Tipsarević (first round) Click on the seed number of a player to go to their draw section.