1985 US Open – Mixed doubles

Manuela Maleeva and Tom Gullikson were the defending champions but lost in the second round to Kathleen Horvath and Leif Shiras.

Martina Navratilova and Heinz Günthardt won in the final 6–3, 6–4 against Elizabeth Smylie and John Fitzgerald.

Seeds
Champion seeds are indicated in bold text while text in italics indicates the round in which those seeds were eliminated.

• # 🇺🇸 Martina Navratilova / Heinz Günthardt (champions)

• # 🇦🇺 Elizabeth Smylie / 🇦🇺 John Fitzgerald (final)

• # 🇦🇺 Wendy Turnbull / 🇬🇧 John Lloyd (semifinals)

• # 🇺🇸 Kathy Jordan / 🇺🇸 Steve Denton (first round)

• # 🇺🇸 Paula Smith / 🇺🇸 Gary Donnelly (quarterfinals)

• # 🇧🇬 Manuela Maleeva / 🇺🇸 Tom Gullikson (second round)

• # Hana Mandlíková /  Ilie Năstase (second round)

• # 🇵🇪 Laura Gildemeister / Hans Gildemeister (first round)