2006 Ordina Open – Women's singles

Klára Koukalová was the defending champion, but lost in second round to Michaëlla Krajicek.

Unseeded Michaëlla Krajicek won the title by defeating Dinara Safina 6–3, 6–4 in the final.

Seeds
The first two seeds received a bye into the second round. • # 🇷🇺 Elena Dementieva (semifinals)

• # 🇷🇺 Dinara Safina (final)

• # 🇮🇹 Flavia Pennetta (first round)

• # 🇷🇺 Maria Kirilenko (first round)

• # Ana Ivanovic (quarterfinals)

• # 🇪🇸 Anabel Medina Garrigues (first round)

• # 🇦🇷 Gisela Dulko (second round)

• # Jelena Janković (quarterfinals, retired due to a left abductor strain)