2016 French Open – Women's doubles

Caroline Garcia and Kristina Mladenovic defeated Ekaterina Makarova and Elena Vesnina in the final, 6–3, 2–6, 6–4 to win the women's doubles tennis title at the 2016 French Open. Garcia and Mladenovic became the first all-French pair to win the title since Gail Sherriff Chanfreau and Françoise Dürr in 1971, and the first of any Frenchwomen since Mary Pierce in 2000, partnering Martina Hingis.

Bethanie Mattek-Sands and Lucie Šafářová were the defending champions, but lost in the first round to Kiki Bertens and Johanna Larsson.

Martina Hingis and Sania Mirza were attempting to complete a non-calendar-year Grand Slam, but lost in the third round to Barbora Krejčíková and Kateřina Siniaková. It would have been Hingis' second non-calendar-year Grand Slam, following her first in 1998–99, and also would have completed a triple career Grand Slam in women's doubles.

This marked the first major main draw appearance of the team of Krejčíková and Siniaková; they reached the semifinals before losing to Makarova and Vesnina.

Seeds
• Martina Hingis / 🇮🇳 Sania Mirza (third round)

• 🇺🇸 Bethanie Mattek-Sands / 🇨🇿 Lucie Šafářová (first round)

• Chan Hao-ching /  Chan Yung-jan (quarterfinals)

• 🇭🇺 Tímea Babos / 🇰🇿 Yaroslava Shvedova (third round)

• 🇫🇷 Caroline Garcia / 🇫🇷 Kristina Mladenovic (champions)

• 🇨🇿 Andrea Hlaváčková / 🇨🇿 Lucie Hradecká (quarterfinals)

• 🇷🇺 Ekaterina Makarova / 🇷🇺 Elena Vesnina (final)

• 🇺🇸 Raquel Atawo / 🇺🇸 Abigail Spears (second round)

• 🇨🇳 Xu Yifan / 🇨🇳 Zheng Saisai (quarterfinals)

• 🇩🇪 Julia Görges / 🇨🇿 Karolína Plíšková (third round)

•  Andreja Klepač /  Katarina Srebotnik (third round)

• 🇪🇸 Lara Arruabarrena / 🇮🇹 Sara Errani (first round)

• 🇪🇸 Anabel Medina Garrigues / 🇪🇸 Arantxa Parra Santonja (first round)

• 🇷🇴 Irina-Camelia Begu / 🇷🇴 Monica Niculescu (withdrew)

• 🇺🇸 Vania King / 🇷🇺 Alla Kudryavtseva (first round)

•  Chuang Chia-jung /  Hsieh Su-wei (first round)