2016 Miami Open – Men's doubles

Bob and Mike Bryan were the two-time defending champions, but lost in the semifinals to Pierre-Hugues Herbert and Nicolas Mahut.

Herbert and Mahut went on to win the title, defeating Raven Klaasen and Rajeev Ram in the final, 5–7, 6–1, [10–7].

Seeds
• # Jean-Julien Rojer / 🇷🇴 Horia Tecău (first round)

• # Ivan Dodig / 🇧🇷 Marcelo Melo (second round)

• # 🇬🇧 Jamie Murray / 🇧🇷 Bruno Soares (first round)

• # 🇺🇸 Bob Bryan / 🇺🇸 Mike Bryan (semifinals)

• # 🇫🇷 Pierre-Hugues Herbert / 🇫🇷 Nicolas Mahut (champions)

• # 🇮🇳 Rohan Bopanna / 🇷🇴 Florin Mergea (first round)

• # 🇫🇷 Édouard Roger-Vasselin / 🇷🇸 Nenad Zimonjić (first round)

• # 🇨🇦 Vasek Pospisil / 🇺🇸 Jack Sock (first round)