2016 Italian Open – Men's doubles

Pablo Cuevas and David Marrero were the defending champions, but Marrero chose not to participate this year. Cuevas played alongside Marcel Granollers, but lost in the quarterfinals to Vasek Pospisil and Jack Sock. Bob and Mike Bryan won the title, defeating Pospisil and Sock in the final, 2–6, 6–3, [10–7].

Seeds
All seeds receive a bye into the second round. • # 🇫🇷 Pierre-Hugues Herbert / 🇫🇷 Nicolas Mahut (withdrew)

• # Ivan Dodig / 🇧🇷 Marcelo Melo (second round)

• # Jean-Julien Rojer / 🇷🇴 Horia Tecău (second round)

• # 🇬🇧 Jamie Murray / 🇧🇷 Bruno Soares (quarterfinals)

• # 🇺🇸 Bob Bryan / 🇺🇸 Mike Bryan (champions)

• # 🇮🇳 Rohan Bopanna / 🇷🇴 Florin Mergea (semifinals)

• # 🇦🇹 Alexander Peya / 🇷🇸 Nenad Zimonjić (second round)

• # 🇨🇦 Vasek Pospisil / 🇺🇸 Jack Sock (final)