2022 Wimbledon Championships – Mixed doubles

Defending champions Neal Skupski and Desirae Krawczyk defeated Matthew Ebden and Samantha Stosur in the final, 6–4, 6–3 to win the mixed doubles tennis title at the 2022 Wimbledon Championships. It was Skupski's second major title, and Krawczyk's fourth. They were the first team to win consecutive mixed doubles titles at Wimbledon since Cyril Suk and Helena Suková in 1997.

This was the first edition of the tournament to feature a champions tie-break (10-point tie-break), when the score reaches six games all in the third set, and the third edition to feature a final set tie-break. Mate Pavić, Sania Mirza, David Vega Hernández and Natela Dzalamidze were the first players to contest this tiebreak in the mixed doubles event, with the team of Pavić and Mirza winning the tiebreak 10–3 in their first-round match.

This was also the first edition of the mixed doubles event to feature 32 instead of 48 teams, and thus five instead of six rounds, with the final moved earlier from the last Sunday of competition to the last Thursday.

Mirza was attempting to complete the career Grand Slam, but was defeated in the semifinals by Skupski and Krawczyk.

Seeds
• # Jean-Julien Rojer / 🇯🇵 Ena Shibahara (second round)

• # 🇬🇧 Neal Skupski / 🇺🇸 Desirae Krawczyk (champions)

• # 🇫🇷 Nicolas Mahut / 🇨🇳 Zhang Shuai (second round)

• # 🇦🇺 John Peers / 🇨🇦 Gabriela Dabrowski (quarterfinals)

• # Marcelo Arévalo / 🇲🇽 Giuliana Olmos (first round)

• # Mate Pavić / 🇮🇳 Sania Mirza (semifinals)

• # 🇨🇴 Robert Farah / Jeļena Ostapenko (quarterfinals)

• # 🇸🇰 Filip Polášek / Andreja Klepač (second round)

Wild cards
• Ivan Dodig /  Latisha Chan

• 🇬🇧 Kyle Edmund / 🇬🇧 Olivia Nicholls

• 🇬🇧 Jamie Murray / 🇺🇸 Venus Williams

• 🇬🇧 Jonny O'Mara / 🇬🇧 Alicia Barnett

• 🇬🇧 Ken Skupski / 🇬🇧 Heather Watson

Protected ranking
• 🇵🇱 Łukasz Kubot / 🇺🇦 Marta Kostyuk

• 🇫🇷 Édouard Roger-Vasselin / 🇫🇷 Alizé Cornet

Alternates
• 🇷🇸 Nikola Ćaćić / 🇷🇸 Aleksandra Krunić

• 🇧🇪 Joran Vliegen / 🇳🇴 Ulrikke Eikeri

Withdrawals

 * 🇵🇱 Łukasz Kubot / 🇺🇦 Marta Kostyuk → replaced by 🇷🇸 Nikola Ćaćić / 🇷🇸 Aleksandra Krunić
 * 🇬🇧 Ken Skupski / 🇬🇧 Heather Watson → replaced by 🇧🇪 Joran Vliegen / 🇳🇴 Ulrikke Eikeri